ea0022p360 | Diabetes | ECE2010
Favaro Enrica
, Zanone Maria Maddalena
, Miceli Ilaria
, Settanni Fabio
, Camussi Giovanni
, Perin Paolo Cavallo
, Ghigo Ezio
, Granata Riccarda
Pancreatic islet microendothelium exhibits unique structural and functional features, in an interdependent physical and functional relationship with the neighbouring β-cells. Glucose toxicity is not solely restricted to β-cells, but affects also survival, proliferation of human pancreatic islet endothelial cells, thus possibly contributing to β-cell function impairment and β-cell loss. It has been previously demonstrated that the ghrelin gene derived peptid...